%0 Journal Article
%T An exploratory clinical study of p38¦Á kinase inhibition in Alzheimer's disease
%A Adriaan Lammertsma
%A Alida Gouw
%A Alle Meije Wink
%A Bart N. M. van Berckel
%A Hui©\May Chu
%A John Alam
%A Maqsood Yaqub
%A Niels Prins
%J Archive of "Annals of Clinical and Translational Neurology".
%D 2018
%R 10.1002/acn3.549
%X The aim of this study was to preliminarily evaluate an oral small molecule p38¦Á kinase inhibitor in patients with early Alzheimer's disease (AD) for the effects on brain amyloid plaque load and episodic memory function, and to establish pharmacokinetic¨Cpharmacodynamics correlations if any effects identified on these parameters
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899915/