%0 Journal Article
%T Autoimmune-related nasal septum perforation: A case report and systematic review
%A Farhoud Faraji
%A Joseph D. Brunworth
%A Kunjan Patel
%A Lohitha Guntupalli
%J Archive of "Allergy & Rhinology".
%D 2017
%R 10.2500/ar.2017.8.0191
%X Inflammatory injury of nasal respiratory mucosa is a common feature of multisystem autoimmune disease. Certain autoimmune disorders are associated with nasal septum perforation (NSP). We performed a systematic review of the literature to better understand the association of NSP with specific autoimmune disorders. This is a case report of a 29-year-old woman with a history of arthralgia, autoreactive antibody titers, platelet dysfunction, and NSP. The constellation of symptoms and potential familial involvement indicated that the NSP in this patient was an early sign of an autoimmune disorder, an unknown autoimmune disorder, or a known disease with incomplete penetrance
%K Nasal septum perforation
%K antinuclear antibody
%K autoimmune
%K perforated nasal septum
%K Wegener granulomatosis
%K relapsing polychondritis
%K cocaine-induced midline lesions
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380452/