%0 Journal Article %T Semi-nonparametric modeling of topological domain formation from epigenetic data %A Emre Sefer %J Archive of "Algorithms for Molecular Biology : AMB". %D 2019 %R 10.1186/s13015-019-0142-y %X We note that (6) is convex, but it is a nonsmooth optimization problem because of the regularizer. We solve it efficiently by using an iterative algorithm from multiple kernel learning [23]. By Cauchy-Schwarz inequality %K Chromatin %K Conformation %K Capture %K Topological domains %K Epigenetic modifications %K Prediction %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399866/