%0 Journal Article
%T In£¿vitro degradation of ¦Â-amyloid fibrils by microbial keratinase
%A Debashis Mukhopadhyay
%A Elangbam Shanta Singh
%A Keising Tamreihao
%A Laishram Jaya Devi
%A Rakhi Khunjamayum
%A Saikat Mukherjee
%A Sumita Banerjee
%J Archive of "Alzheimer's & Dementia : Translational Research & Clinical Interventions".
%D 2019
%R 10.1016/j.trci.2019.03.003
%X Amyloid fibrils are misfolded, protease-resistant forms of normal proteins. They are infectious such as prions or noninfectious such as ¦Â-amyloid (A¦Â) fibrils causing Alzheimer's disease (AD). Prions and amyloids are structurally similar, possessing cross ¦Â-pleated sheet-like structures. As microbial keratinase could degrade prions, we tested keratinase activity on A¦Â fibrils
%K Actinomycete
%K Keratinase
%K ¦Â-amyloid fibrils
%K Ker 1
%K In vitro degradation
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527806/