%0 Journal Article %T Synergism of antihypertensives and cholinesterase inhibitors in Alzheimer's disease %A James Becker %A Levent Kirisci %A Lirong Wang %A M. Ilyas Kamboh %A Qianzhou Lv %A Robert A. Sweet %A Shifan Ma %A William E. Klunk %A Xiang-Qun Xie %A Ying Xue %A Zhiwei Feng %A Ziheng Hu %J Archive of "Alzheimer's & Dementia : Translational Research & Clinical Interventions". %D 2018 %R 10.1016/j.trci.2018.09.001 %X We investigated the effect of antihypertensive (aHTN) medications and cholinesterase inhibitors (ChEIs) on the cognitive decline in patients with Alzheimer's disease (AD) and analyzed synergism by chemogenomics systems pharmacology mapping %K Alzheimer's disease %K Cognitive decline %K Cholinesterase inhibitors %K Antihypertensive medications %K Combination therapy %K Systems pharmacology %K Clinical data mining %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205113/