%0 Journal Article %T Altered expression of insulin-degrading enzyme and regulator of calcineurin in the rat intracerebral streptozotocin model and human apolipoprotein E-¦Å4¨Cassociated Alzheimer's disease %A B¨¹£¿ra Delikkaya %A Gina Gallucci %A Ming Tong %A Natalia Moriel %J Archive of "Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring". %D 2019 %R 10.1016/j.dadm.2019.03.004 %X This study assesses insulin-degrading enzyme (IDE) and regulator of calcineurin 1 (RCAN1) as potential mediators of brain insulin deficiency and neurodegeneration in experimental and human Alzheimer's disease (AD) %K Alzheimer's disease %K Insulin deficiency %K Insulin resistance %K Streptozotocin %K Insulin-degrading enzyme %K RCAN1 %K Neurodegeneration %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522644/