%0 Journal Article
%T Differential Methylation of Syncytin-1 and 2 Distinguishes Fetal Growth Restriction from Physiologic Small for Gestational Age
%A Katherine P. Himes
%A Sami P. Makaroun
%J Archive of "AJP Reports".
%D 2018
%R 10.1055/s-0038-1627473
%X Objective £¿The retroviral genes encoding Syncytin-1 ( SYN1 ) and Syncytin-2 ( SYN2 ) are epigenetically regulated, uniquely expressed in the placenta and critical to placental function. We sought to determine if placental expression and methylation patterns of SYN1 and SYN2 from pregnancies complicated by fetal growth restriction (FGR) differed from physiologic small for gestational age (SGA) and appropriate for gestational age (AGA) controls
%K retroelements
%K syncytin
%K methylation
%K placenta
%K fetal growth restriction
%K intrauterine growth restriction
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821508/