%0 Journal Article
%T Integrating Medication Alert Data into a Clinical Data Repository to Enable Retrospective Study of Drug Interaction Alerts in Clinical Practice
%A Brittany L. Melton
%A Gregory Ator
%A Lemuel R. Waitman
%A Mei Liu
%J Archive of "AMIA Summits on Translational Science Proceedings".
%D 2017
%X Current clinical data repositories primarily extract data from multiple administrative and electronic medical record (EMR) data resources (e.g., hospital and physician billing records) containing specific patient-level data including demographics, medications, laboratory results, diagnoses, and procedure codes. It overlooks the importance of EMR system-level data (e.g., medication alerts that are routinely used by physicians, nurses, and pharmacists for decision support) for the surveillance of EMR decision support tools. These medication alerts are a significant source of information for providers, to minimize avoidable adverse drug events. This study describes the integration of medication alert data into an i2b2-based clinical data repository to support the investigation of clinical events occurring around patients with anticoagulation treatment that triggered drug-drug interaction alerts. The integration of medication alerts allows us to repurpose the clinical and translational research infrastructure to conduct retrospective effectiveness surveillance of clinical decision support tools
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543377/