%0 Journal Article %T Denosumab Treatment for Aggressive Multiple Recurrent Familial Central Giant-cell Granulomas %A Aleksi RytkŁżnen %A Eelis RytkŁżnen %A George K. S¨˘ndor %A Petri Lehenkari %A Sanna Uusitalo %A Vuokko Ottavainen %J Archive of "Annals of Maxillofacial Surgery". %D 2018 %R 10.4103/ams.ams_192_18 %X Aggressive familial giant-cell granulomas of the jaws can be severely deforming. Surgical and nonsurgical treatments may be associated with multiple recurrences. Denosumab, a new generation antiresorptive drug, is an osteoclast inhibitor, which may be particularly useful to manage such potentially disfiguring lesions %K Central giant-cell granuloma %K denosumab %K familial %K mandible %K maxilla %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327812/