%0 Journal Article
%T Bioactive isochromenone isolated from Aspergillus fumigatus, endophytic fungus from Bacopa monnieri
							| Microbiology Research
%A Alok Kalra
%A Arvind S. Negi
%A Balagani Sathish Kumar
%A Dhananjay Kumar Singh
%A Dharmendra Saikia
%A Jay Prakash Thakur
%A Prema G. Vasudev
%A Rumana Haider
%A Suaib Luqman
%J Microbiology Research
%D 2015
%R https://doi.org/10.4081/mr.2015.5800
%X Fungal endophytes are a significant reservoir of novel bioactive secondary metabolites. Present communication describes isolation and structure determination of isochromenone, from endophytic microorganism Aspergillus fumigatus hosted in Bacopa monnieri plant. Further, its biological evaluation revealed it as antioxidant and antitubercular. The methanol extract of A. fumigatus inhibits the growth of the virulent strain of Mycobacterium tuberculosis H37RV with minimum inhibitory concentration 500 ¦Ìg/mL. This is the first report of isolation of isochromenone from A. fumigatus
%K Bacopa monnieri
%K Aspergillus fumigatus
%K endophyte
%K isochromenone
%K antioxidant
%U https://www.pagepress.org/journals/index.php/mr/article/view/5800