%0 Journal Article %T Resistance of uropathogens to antibacterial agents: Emerging threats, trends and treatments | Archivio Italiano di Urologia e Andrologia %A Alberto Trinchieri %A Emanuele Montanari %A Gianpaolo Perletti %A Konstantinos Stamatiou %A Tommaso Cai %A Vittorio Magri %J Archivio Italiano di Urologia e Andrologia %D 2018 %R https://doi.org/10.4081/aiua.2018.2.85 %X Urinary tract infections are among the most common infectious diseases in humans. Today, resistance to nearly all antimicrobial classes is dramatically growing, and extremely drug-resistant or even pan-drug resistant pathogens are increasingly isolated around the world. It is foreseen that in the next decades the world will be facing a major medical emergency generated by the rapid spread of pathogens carrying resistance determinants of unprecedented power. Carbapenemase-producing Enterobacteriaceae, multidrug- resistant Enterococci and fluoroquinolone resistance determinants in both Gram-negative and Gram-positive uropathogens are among the greatest emergencies. In this article, the major emerging threats of particular interest to urologists are reviewed, worldwide resistance trends are illustrated, and novel and older ¨C but still active ¨C recommended drugs are summarized %K Urinary tract infections %K Resistance %K Antibacterial agents %K Antibiotics %K Carbapenemase %K Carbapenem resistance %U https://www.pagepressjournals.org/index.php/aiua/article/view/aiua.2018.2.85