%0 Journal Article
%T Intestinal IL-17 Expression in Canine Inflammatory Bowel Disease
%A Azuma YT
%A Fujimoto Y
%A Kuramoto N
%A Miki M
%A Nishiyama K
%A Kinjo T
%J Veterinary Health Science & Research (IJVHSR)
%D 2018
%R http://dx.doi.org/10.19070/2332-2748-1700035
%X Abstract IL-17 plays important roles in human inflammatory bowel disease (IBD). However, little is known about the possible relation of IL-17 in canine IBD. For comparative medicine and canine disease, it is useful to demonstrate the role of IL-17 in canine IBD. In this study, 7 cases of the dog with IBD typed of lymphocytic-plasmacytic enteritis without Intestinal lymphoma were examined immunohistochemically for possible relation with IL-17. Here, we found that IL-17 is expressed in intestinal mucosa of the dog with IBD. Among 7 cases, there are strong expressions of IL-17 in cases 2, moderate expression of it in cases 2, weak expression of it in cases 2, and very low expression of it in case 1. The score of IL-17 expression is not correlated with sex, age, and the breed. Using biopsy specimen, our results revealed the immunopathological relevance of IL-17 in the dog with IBD
%K n/a
%U https://scidoc.org/IJVHSR-2332-2748-05-301.php