%0 Journal Article %T 食管癌三维适形放疗GTV-T体积与临床分期及预后的相关性分析 %A 刘志坤 %A 李娟 %A 沈文斌 %A 祝淑钗 %A 苏景伟 %J 肿瘤防治研究 %D 2015 %R 10.3971/j.issn.1000-8578.2015.07.011 %X 摘要 目的 探讨应用肿瘤体积大小评价食管癌临床分期标准的准确性、符合程度及其与预后的关系。方法 分析接受根治性三维适形放疗(three-dimensional conformal radiotherapy, 3DCRT)的375例食管癌患者临床资料,选择合适的GTV-T体积分级标准,结合区域淋巴结转移情况进行临床分期,并结合患者预后进行分析。结果 与病理T分期对应,将GTV-T体积按≤30 cm3、30~≤60 cm3、60~90cm3、>90 cm3分为T1、T2、T3、T4四级,5年生存率之间比较,T3与T4级之间差异无统计学意义(P=0.556),而按T1、T2、T3+4三分级,各T分级之间的生存差异有统计学意义(P<0.001)。无区域淋巴结转移N0者较有区域或非区域淋巴结转移N1~2者预后好(P=0.000)。对应GTV-T体积T1、T2、T3+4三分级,将食管癌临床分期对应分为Ⅰ、Ⅱ、Ⅲ期,将出现N2期或远处转移的患者,全部归入Ⅳ期,各期生存差异具有统计学意义(P<0.001)。结论 GTV-T按T1、T2、T3+4三分级法能较好地反映预后生存;对应GTV-T三分级的临床四分期法,亦能较好的反应预后 %K Partial Versus Radical Nephrectomy %K Upper Gastrointestinal Carcinomas Incidence from 2003 to 2012 in Cixian %K Hebei Province %K Prognostic Value of Circulating Tumor Cells for Metastatic Prostate Cancer: A Metaanalysis %K Correlation of CD68+ Tumor-associated Macrophages Number with Ki-67 Expression and Prognosis of Patients with Primary Hepatocellular Carcinoma %K Relationship of Macrophage Migration Inhibitory Factor Expression with Clinicopathologic Features and Prognosis of Cardiac Carcinoma Patients %K Advance of Prognostic Markers of Cervical Cancer %K Metaplastic Carcinoma of Breast with Mesenchymal Differentiation: 28 Cases Report %K Epidemiologic Investigation on Mortality Due to Esophagus Cancer in Residents in Xiamen %K 2005-2014 %U http://www.zlfzyj.com/CN/abstract/abstract8540.shtml