%0 Journal Article
%T 2型糖尿病和血小板计数在原发性肝癌患者中的关系研究
%A 张伟硕
%A 房龙
%A 高春
%J 肿瘤防治研究
%D 2016
%R 10.3971/j.issn.1000-8578.2016.05.011
%X 摘要 目的 探讨2型糖尿病和血小板计数在原发性肝癌患者中的关系。方法 采用横断面研究，按照诊断标准、纳入和排除标准，研究纳入2003年1月至2012年4月在中日友好医院住院且以“原发性肝癌”作为主要诊断的患者375例。分析入选患者的人口统计学、临床、生化、代谢等资料，二元非条件Logistic回归分析研究2型糖尿病和血小板计数在原发性肝癌患者中的关系。结果 375例患者中，63例（16.8%）合并2型糖尿病，患者的平均白细胞计数（4.13±2.49）×109/L，血红蛋白定量（132.5±23.8）g/L，血小板计数的中位数和四分位数间距130/（85~189）×109/L，国际标准化比值（1.20±0.27）。两组比较的结果提示，血小板计数[113/（64~157）×109/L vs. 139/（89~192）×109/L, P=0.020]在两组人群中差异存在统计学意义。多因素分析的结果显示，在控制年龄、乙肝感染、血红蛋白定量和INR等情况下，血小板计数不是原发性肝癌合并2型糖尿病患者的独立相关因素，OR值为0.999，95%CI: 0.995~1.003（P=0.505）。结论 原发性肝癌合并2型糖尿病患者的血小板计数明显低于肝癌不合并糖尿病患者，Logistic回归分析归因于其他因素的作用
%K A Case Report
%K Emergency Transcatheter Arterial Embolization Combined with Two-stage Liver Resection for Spontaneous Ruptured Hepatocellular Carcinoma: A Systematic Review
%K Microwave Ablation Combined with Stereotactic Radiotherapy for Primary and Recurrent Hepatocellular Carcinoma after Interventional Treatment
%K Meta-analysis on Relationship between runx3 Gene and Hepatocellular Carcinoma
%K Clinical Effects of Yanshu on Primary Hepatic Carcinoma Treated with Interventional Therapy
%K Correlation of MMP-9 and MMP-2 Gene SNPs with Hepatocellular Carcinoma Invasion and Metastasis
%K Prevention and Treatment of Complications after Argon-helium Cryoablation on Primary Hepatocarcinoma
%K Percutaneous Microwave Coagultion Therapy Influence on Hepatofibrosis of Primary Hepatocellular Carcinoma Serum
%K Survival Analysis of 108 Cases with Advanced Primary Liver Cancer Treated by Transcatheter Arterial Chemoembolization
%K Comparative Analysis of Aetiology Clustering of Hepatocellular Carcinoma between Two Families with High Mortality of Hepatocellular Carcinoma Discovered Recently in Guangxi Region
%K Role of Antiviral Therapy Using Lamivudin in Treatment of Primary Liver Cancer Complicated by Hepatitis B Virus
%K Analysis of Virological Characteristics on HBeAg Positive Primary Hepatic Carcinoma
%K Association between Diabetes Mellitus and Hepatocellular Carcinoma: A Meta- analysis of Cohort Study
%U http://www.zlfzyj.com/CN/abstract/abstract8749.shtml