%0 Journal Article
%T 食管鳞状细胞癌中miRNAs的研究进展
%A 张聪
%A 戴天阳
%J 肿瘤防治研究
%D 2015
%R 10.3971/j.issn.1000-8578.2015.02.023
%X 摘要 食管鳞状细胞癌（esophageal squamous cell carcinoma, ESCC）是我国常见食管癌（esophageal cancer, EC）的主要亚型。虽然ESCC从分子遗传学角度已被广泛研究，但其发病分子机制还没有完全阐明。microRNAs（miRNAs）是一类小的内源性非蛋白编码RNAs，在生理、病理过程中发挥着重要作用，包括细胞分化、凋亡、增殖和代谢。miRNAs通过致癌基因、抑癌基因在ESCC的发病机制中扮演着重要角色。近年来研究表明，许多miRNAs在ESCC组织中的表达存在明显的差异，了解miRNAs及其靶基因在ESCC发生发展中的作用，可能为早期检测、诊断、治疗和预后提供策略
%K miRNAs
%K 食管鳞状细胞癌
%K 靶基因
%K Expression of EZH2 and H3K27me3 in Esophageal Squamous Cell Carcinoma and Their Significance
%K Metastasis?associated Lung Adenocarcinoma Transcript1(MALAT1) Expression in Middle Thoracic Esophageal Squamous Cell Cancer Tissues and Its Relationship with Prognosis
%K Support Vector Machine Predicts Survival of Esophageal Squamous Cell Carcinoma Patients
%K Progress on Functional Investigation of 3’UTR SNPs in MicroRNA Targeting Genes Associated with Lung Cancer
%K Recent Advance on MicroRNA-320 in Tumors
%K Tumor Suppressor Roles of miR-100 in Esophageal Squamous Cell Carcinoma Cell Line Ec-109
%K Screening of Differential DNA Methylation Profile and Construction of Aberrant Methylation Panel in Esophageal Squamous Cell Carcinoma
%K Advances of Aberrant miRNAs Expression in Multiple Myeloma
%K Expression of Metastasis Suppressor Gene KiSS-1 in Esophageal Squamous Cancer and Its Clinical Significance
%K Clinical Characteristics of Promoter Hypermethylation of PTEN Gene in Esophageal Carcinoma Tissues
%K Progress on Osteosarcoma Pathogenesis
%K Study Advancement of MicroRNA and Its Target Gene Polymorphism and Colorectal#br# Tumorigenesis
%K Expression and Signifi cance of PIRH2 and P53 Proteins in Esophageal Squamous Cell#br# Carcinoma Tissues
%K Expression and Bioinformatics Analysis of hsa-miR-133a in Cell Lines of Human#br# Esophageal Squamous Cell Carcinoma
%U http://www.zlfzyj.com/CN/abstract/abstract8431.shtml