%0 Journal Article
%T NF-κB相关分子通路在弥漫大B细胞淋巴瘤中的研究现状
%A 林丽珠
%A 翟林柱
%A 赵媛媛
%J 肿瘤防治研究
%D 2016
%R 10.3971/j.issn.1000-8578.2016.10.015
%X 摘要 随着新一代基因检测技术的出现，弥漫大B细胞淋巴瘤的分子通路及相关基因变异研究越来越深入。NF-κB的激活是这些通路活化过程中的关键事件，研究揭示了NF-κB相关通路在弥漫大B细胞淋巴瘤中异常激活，发现了新的与肿瘤发生有关的信号通路和基因突变，并为临床进行治疗干预提供了新的靶点
%K 弥漫大B 细胞淋巴瘤
%K 分子亚型
%K 信号通路
%K 基因突变
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%U http://www.zlfzyj.com/CN/abstract/abstract8858.shtml