%0 Journal Article
%T 微小RNAs在良恶性胸腔积液中的研究进展
%A 刘崇梅
%A 王彩霞
%A 阳娟
%J 肿瘤防治研究
%D 2015
%R 10.3971/j.issn.1000-8578.2015.04.018
%X 摘要 microRNAs(miRNAs）是长度为19~24 nt的非编码小RNA，可通过与其靶mRNA特异性结合导致mRNA降解或翻译抑制，从而负向调控基因表达。miRNAs参与包括细胞分化、增殖、凋亡等一系列重要细胞活动的调控。miRNAs的异常表达与人类肿瘤密切相关。miRNAs具有较强的稳定性，广泛存在人体组织、体液中。本文就miRNAs在胸腔积液中的研究进展作一综述，以期为良恶性胸腔积液的鉴别等提供新的概念及思路
%K 微小RNAs
%K 良恶性胸腔积液
%K 表达
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%K Correlation of ChREBP mRNA Expression and Its CpG Island Methylation in Human Hepatocellular Carcinoma
%K Research Progress of circRNAs in Cancer
%K LncRNA Colorectal Neoplasia Differentially Expressed(CRNDE) Regulated Cell Proliferation and Migration in Glioma
%K Identification of Gene Signature in Peripheral Blood of Breast Cancer
%K Replication-deficient Adenovirus Carrying hsa-microRNA-149 Inhibits Proliferation of Human Hepatocellular Carcinoma Cell Lines
%K Clinical Value of miRNAs in Blood or Sputum as Biomarkers for Early Screening and Diagnosis of Lung Cancer
%K Molecular Classification of Triple Negative Breast Cancer and Its Applications
%K Differential Expressions of microRNAs in Rectal Adenocarcinoma Tissues
%K Establishment of Hepatocellular Carcinoma Cell Line HepG2 Stably Transfected by Hepatitis B Virus X Gene and Its Effects on p53-p21 Pathway
%K Recombinantion
%K Expression and Purifi cation of Cancer Testis Antigen GAGE-1
%K Bioinformatics-based Analysis for microRNAs Expression Profiles between Basal-like and Luminal A Breast Cancers
%K Expression and Clinical Significance of CIP2A in Bladder Urothelial Cell Carcinoma
%K Predict Metastasis Risk of Lymph Node-negative Breast Cancer by Combination 32 Gene Expression Profiles with Clinical and Pathological Data
%U http://www.zlfzyj.com/CN/abstract/abstract8474.shtml