%0 Journal Article %T 预防性放疗降低恶性胸膜间皮瘤有创操作通道转移发生率的Meta分析 %A 任庆兰 %A 刘雪 %A 谭春燕 %A 黄月 %J 肿瘤防治研究 %D 2018 %R 10.3971/j.issn.1000-8578.2018.17.1267 %X 摘要 目的 系统评价预防性放疗能否降低恶性胸膜间皮瘤(MPM)有创操作通道转移(PTMs)发生率。方法 检索PubMed、Cochrane Library、Web of Science、Embase数据库,收集MPM有创操作通道进行预防性放疗的相关研究,由两位评价员独立筛选文献、提取资料并评价纳入研究的方法学质量后,采用RevMan5.3软件进行Meta分析。结果 共纳入7项研究,包括698例患者。Meta分析结果显示,预防性放疗不能降低所有MPM患者PTMs的发生率(OR=0.48, 95%CI: 0.22~1.07, P=0.07)。而进行亚组分析后发现预防性放疗能有效减少进行大口径操作的MPM患者(OR=0.39, 95%CI: 0.18~0.84, P=0.02),或上皮型MPM患者(OR=0.21, 95%CI: 0.11~0.69, P=0.006)医源性PTMs的发生。结论 预防性放疗能有效预防进行开胸手术、胸腔镜、留置胸壁引流管等大口径操作或病理类型为上皮型MPM患者医源性PTMs的发生 %K A Meta-analysis %K Meta-analysis of Efficacy and Safety of Jinlong Capsule Combined with Chemoradiotherapy on Liver Metastases %K Comparison of Efficacy Between S-1 and Capecitabine/Fluorouracil on Advanced Colorectal Cancer: A Meta-analysis %K Prognostic and Clinicopathological Significance of PD-L1 Expression for Colorectal Cancer: A Meta-analysis %K Correlation Between Coke Oven Emissions and Death of Occupational Lung Cancer: A Meta-analysis %K Efficacy and Safety of PD-1/PD-L1 Inhibitor Versus Chemotherapy in First-line Treatment of Advanced Non-small Cell Lung Cancer: A Meta-analysis %K Clinicopathological and Prognostic Value of Circulating Tumor Cells in Peripheral Blood in Head and Neck Cancer Patients: A Meta-analysis %K Prognostic Significance of Platelet-lymphocyte Ratio in Hepatocellular Carcinoma Patients: A Meta-analysis %K Prognostic Value of Completion Lymph Node Dissection on Melanoma Patients with Positive Sentinel Lymph Node Biopsy: A Meta-analysis %K Relationship of Para-aortic Lymph Nodes (PALN) Status with Prognosis and Clinicopathological Features of Pancreatic Cancer Patients After Pancreatectomy %K A Meta-analysis on Relationship of Dietary Factors with Liver Cancer in Chinese Population %K Effect of FDG-PET/CT in Diagnosis %K Staging and Prognosis of Pancreatic Cancer: A Meta-analysis %K Laparoscope Versus Laparotomy in Treatment of Early-stage Cervical Cancer: A Systematic Review %K Meta-analysis of Long-term Survival of Extended and Standard Pancreaticoduodenectomy for Carcinoma of Head of Pancreas with Positive Lymph Nodes %K Prognostic Value of Circulating Tumor Cells for Metastatic Prostate Cancer: A Metaanalysis %U http://www.zlfzyj.com/CN/abstract/abstract9151.shtml