%0 Journal Article %T 国际肺癌研究协会第八版国际肺癌TNM分期修订稿解读 %A 张用 %A 曾凡玉 %A 毕建平 %A 皮国良 %A 胡德胜 %A 韩光 %J 肿瘤防治研究 %D 2016 %R 10.3971/j.issn.1000-8578.2016.04.016 %X 摘要 肺癌导致的死亡人数位于各类恶性肿瘤之首,它是对人类健康和生命威胁最大的恶性肿瘤之一。肺癌的TNM分期系统描述了肺癌的生长和扩散等信息,对于指导其临床治疗起了非常重要的作用。目前临床上广泛采用的是国际抗癌联盟(Union for International Cancer Control, UICC)和美国癌症联合会(American Joint Committee on Cancer, AJCC)于2009年发布的第七版肺癌TNM分期。随着肺癌综合治疗的发展以及临床实践模式的改变,肺癌的疗效及其预后也有了明显的改变,旧的分期标准可能难以满足目前的临床需求。因此,国际肺癌研究协会(international association for the study of lung cancer, IASLC)于2014年就开始进行最新一轮的肺癌TNM分期标准修订研究计划。本次分期研究克服了以往分析数据均为回顾性数据的缺陷,采用囊括了回顾性和前瞻性数据的新数据库。该数据库主要是由1999—2010年间新确诊的94 708名肺癌患者数据组成。通过对该数据库分析研究,国际肺癌研究协会对TNM分期进行了相应的修改,并最终在2015年发表了第八版国际肺癌TNM分期的修订稿。本文就该修订稿的细节进行解读 %K A Meta-analysis %K Effect of Rap2a on Invasion and Metastasis of Lung Cancer Cells and Its Related Mechanism %K NSCLC的疫苗治疗研究进展 %K Immune Killing Effect of Silencing TIPE2 Expression on T Lymphocytes Against Lung Adenocarcinoma Cells LA795 %K Clinical Investigation on Qingfei Mixture Combined with Chemotherapy on Middle and Advanced Non-small Cell Lung Cancer %K Effect of Vascular Endothelial Cadherin on Invasion and Metastasis of Non-small Cell Lung Cancer Cells and Related Mechanism %K Advances of FGF/FGFR Signaling Pathway in Targeted Therapy for Squamous Cell Lung Cancer %K Sulforaphane Suppressed Proliferation of Lung Cancer Stem Cells in vitro %K Experiment of Different Administration Sequences of Apatinib and Paclitaxel on Lung Cancer %K Cryptotanshinone Promotes Apoptosis of A549 Cells via Inhibiting Cap-dependent mRNA Translation %K Expressions of MMP-7 mRNA %K sMICA %K VEGF in Peripheral Blood of Lung Cancer Patients and Their Relationships with Invasion and Metastasis %K Quality Assessment of Reports of Randomized Controlled Trials Published in Chinese in Field of Non-small Cell Lung Cancer in China %U http://www.zlfzyj.com/CN/abstract/abstract8737.shtml