%0 Journal Article
%T 晚期上皮性卵巢癌不同治疗方案的预后影响因素分析
%A 刘传忠
%A 李力
%A 王鹤
%A 蔡志福
%A 赵冰冰
%J 肿瘤防治研究
%D 2018
%R 10.3971/j.issn.1000-8578.2018.17.1278
%X 摘要 目的 分析晚期上皮性卵巢癌患者接受传统治疗及新辅助化疗的预后差异，探讨影响患者预后的临床特征。方法 回顾性分析129例晚期上皮性卵巢癌患者临床资料。根据不同治疗方案分为NACT-IDS组（69例）及PDS组（60例）。结果 两组患者平均手术时间、术中出血量、手术并发症的发生率及术后住院日差异均无统计学意义（P>0.05）。NACT-IDS组及PDS组手术理想减灭率差异有统计学意义（P=0.002）。两组患者平均总生存期及无进展生存期差异均无统计学意义。根据年龄、临床分期、病理学类型等临床特征单独比较接受不同治疗方案的两组患者预后，发现差异均无统计学意义（P>0.05）。将临床特征组合进行评估时，仅接受NACT-IDS及PDS治疗并达到理想减灭的Ⅲ期患者平均总生存时间差异有统计学意义（P=0.030）。结论 对于晚期上皮性卵巢癌，建议经评估可以通过PDS达到理想减灭的Ⅲ期患者行PDS，其余晚期患者可以放宽NACT的实施标准
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%U http://www.zlfzyj.com/CN/abstract/abstract9247.shtml