%0 Journal Article %T 江苏省昆山市1981-2014年胃癌死亡率趋势及率差分解分析 %A 仝岚 %A 史建国 %A 周杰 %A 张婷 %A 秦威 %A 罗晓明 %A 胡文斌 %A 邱和泉 %A 金亦徐 %J 肿瘤防治研究 %D 2016 %R 10.3971/j.issn.1000-8578.2016.05.018 %X 摘要 目的 探究江苏省昆山市1981—2014年胃癌死亡率变化趋势及定量估计影响因素。方法 历年胃癌死亡病例来源于全人群死因监测,计算分性别和年龄组粗死亡率与年龄标化率,使用年度变化百分比(annual percentage change, APC)及其95%CI评价死亡率在1981—2014年时间趋势。采用率差别分解法分析人口因素对胃癌死亡率变化的贡献。结果 胃癌年龄标化死亡率在男女合计(APC=-3.6%, 95%CI: -3.9%~-3.3%)、男性(APC=-3.9%, 95%CI: -4.3%~-3.5%)和女性(APC=-3.5%, 95%CI: -4.0%~-3.0%)人群中呈明显的下降趋势。昆山市1981—2014年间胃癌死亡率0~74岁累积率在男性和女性人群中大幅下降(APC=-4.2%, 95%CI: -4.7%~-3.7%)。胃癌死亡率的下降是人口因素与非人口因素作用结果,其中人口因素贡献在男女合计、男性及女性人群中分别为-124.92%、-154.61%和-117.52%。结论 江苏省昆山市过去30年高水平胃癌死亡率在非人口因素作用下持续下降,但这种下降受到了人口因素的阻碍 %K 2 Matched Case-control Investigation on Risk Factors of Gastric Cancer in Xianyou County %K Epidemiologic Investigation on Mortality Due to Esophagus Cancer in Residents in Xiamen %K 2005-2014 %K Expression of CLIC4 in Gastric Carcinoma Tissues and Its Relevance to Microsatellite Instability %K Mortality Trend of Colorectal Cancer in Kunshan City %K Jiangsu Province %K 1981-2014 %K Efficacy and Safety of Weekly Liposome-paclitaxel or Oxaliplatin Combined with Tegafur on Elderly Advanced Gastric Cancer %K Periplocin Extracted from Cortex Periplocae(CPP) Induced Apoptosis of Gastric Cancer Cells MGC-803 Through Lysosomal Pathway %K Effect of Ubiquitin-like with PHD and Ring Finger Domain 1 on Invasion and Metastasis of Gastric Cancer and Related Mechanism %K Effects of miR-711 on Invasion %K Metastasis and Epithelial Mesenchymal Transition of Gastric Cancer Cells MGC-803 %K Role of p53β Isoform in Inhibitory Effect of rmhTNF Combined with Cisplatin on Human Gastric Cancer Cell Growth %U http://www.zlfzyj.com/CN/abstract/abstract8756.shtml