%0 Journal Article
%T 抑制糖酵解途径治疗结直肠癌的研究进展
%A 孙磊涛
%A 张乐吟
%A 沈敏鹤
%A 阮善明
%J 肿瘤防治研究
%D 2018
%R 10.3971/j.issn.1000-8578.2018.18.0354
%X 摘要 近年来，我国结直肠癌发病率及死亡率逐年上升，寻找早期预防、诊断和治疗的有效途径是目前结直肠癌基础及临床的研究热点。机体正常细胞主要由葡萄糖氧化供能，而结直肠癌细胞的糖酵解途径显著增强并以此作为主要供能途径。本文就糖酵解关键酶、信号转导通路和转录因子在结直肠癌糖酵解途径中的研究进展及治疗策略作一综述
%K A Meta-analysis
%K Relation Between Metabolic Parameters of 18F-FDG PET/CT and Clinicopathological Features of Colorectal Cancer Patients
%K Prognostic and Clinicopathological Significance of PD-L1 Expression for Colorectal Cancer: A Meta-analysis
%K Composition and Laboratory Examination Characteristics of 187 Colorectal Cancer Patients with Schistosomiasis
%K Clinical Effect of Oral Nutritional Supplements in Patients with Colorectal Cancer After Emergency Surgery
%K Effects of NDUFA4 Overexpression on Growth of Human Colon Cancer Cells in vitro
%K Significance of E47 and LOXL2 Expressions in Esophageal Squamous Cell Carcinoma Tissues
%K Effects and Regulatory Mechanisms of SNAI2 on Malignant Hallmarks of Non-Invasive Breast Tumor Cells
%K Influence of TYMP Polymorphism on Clinical Outcomes of Colorectal Cancer Patients Received Adjuvant Chemotherapy After R0 Resection
%K Established of Serum Diagnostic Model for Colorectal Cancer Patients Using MB-WCX and MALDI-TOF MS
%K Mechanism of Bacterial Biofilm Involved in Colorectal Carcinogenesis
%K Construction of Gene-coregulation-network for Osteosarcoma MicroRNA
%K Sensitivity of Esophageal Squamous Carcinoma Cell Line KYSE150 to Cisplatin Can Be Improved by RNA-interfered Expression of IQGAP1
%K Expression and Clinical Significance of Forkhead Box M1 and Polo-like Kinase 1 in Breast Carcinoma Tissues
%K Effect of Down-regulating KLF8 Expression by siRNA on EMT in Nasopharyngeal Carcinoma Cells
%U http://www.zlfzyj.com/CN/abstract/abstract9237.shtml