%0 Journal Article
%T 肿瘤的光遗传学治疗
%A 岳红云
%A 张百红
%J 肿瘤防治研究
%D 2018
%R 10.3971/j.issn.1000-8578.2018.18.0642
%X 摘要 光遗传学技术应用遗传学和光的方法刺激和控制生物组织中特定细胞的功能。自从2005年报道用光照射视蛋白精准控制神经活性以来，光遗传学在肿瘤治疗中的应用初见端倪，其作用机制包括操纵神经元活动、解除免疫抑制、改变细胞内外电压、控制细胞力、调控信号转导、遗传和表观遗传调节以及筛选抗肿瘤药物。未来将通过光刺激改变肿瘤行为，肿瘤光遗传学治疗前途光明
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%U http://www.zlfzyj.com/CN/abstract/abstract9304.shtml