%0 Journal Article
%T 放射性核素标记Exendin-4类似物用于胰岛素瘤显像的研究进展
%A 杨敏
%A 罗世能
%A 许清
%J 肿瘤防治研究
%D 2015
%R 10.3971/j.issn.1000-8578.2015.04.020
%X 摘要 胰岛素瘤是常见的胰腺内分泌肿瘤，常规方法难以检测。核素显像如单光子断层扫描（SPECT）和正电子断层扫描（PET）具有无创、敏感度高、特异性好等优势，为胰岛素瘤的诊断提供了新技术。胰高血糖素样肽-1受体（GLP-1R）在胰岛素瘤中高表达，是潜在的肿瘤靶点。Exendin-4作为GLP-1R激动剂，可与受体特异性结合。本文介绍放射性核素标记GLP-1R激动剂（Exendin-4）类似物的进展及在胰岛素瘤显像研究中的应用
%K 放射性核素
%K 胰高血糖素样肽-1受体
%K Exendin-4
%K 放射性核素显像
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%U http://www.zlfzyj.com/CN/abstract/abstract8476.shtml