%0 Journal Article
%T 肿瘤治疗中Clostridium novyi-NT的研究
%A 丁娜娜
%A 张硕
%A 李明远
%A 石新丽
%J 肿瘤防治研究
%D 2015
%R 10.3971/j.issn.1000-8578.2015.01.018
%X 摘要 联合细菌的溶瘤治疗（combined bacteriolytic therapy，COBALT）策略在实体瘤治疗中方兴未艾。此策略是将专性厌氧菌Clostridium novyi-NT联合传统放化疗药物治疗实体瘤，现处于临床Ⅰ期试验阶段。本文分别从有效性及安全性等方面总结了抗肿瘤细菌应具有的标准，并简述了C. novyi-NT 的溶瘤机制
%K 肿瘤治疗
%K Clostridium novyi-NT
%K 溶瘤细菌
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%U http://www.zlfzyj.com/CN/abstract/abstract8400.shtml