%0 Journal Article
%T 胰腺癌肝转移患者多学科综合治疗临床分析
%A 周勇
%A 李泽朝
%A 罗诗樵
%J 肿瘤防治研究
%D 2015
%R 10.3971/j.issn.1000-8578.2015.02.012
%X 摘要 目的 对胰腺癌肝转移患者的临床特征及不同治疗模式分析，探讨不同治疗模式对患者生存预后的影响。方法 回顾性分析2009年1月至2012年1月重庆医科大学附属第一医院64例胰腺癌肝转移患者的临床资料，对其临床特征和治疗模式分别用Kaplan-Meier法及Cox模型进行单因素及多因素分析。结果 64例患者总的中位生存时间（median survival time, MST）为4月，6月、1年及2年生存率（overall survival, OS）分别为39.1%、21.9%和7.8%。单因素分析显示，年龄、疼痛、厌食、CA19-9水平、ALT和GGT水平、手术、介入化疗栓塞/介入化疗、积极治疗及多学科综合治疗是预后影响因素。多因素分析示：肝外转移、疼痛、CA19-9、积极治疗、手术、介入化疗栓塞/介入化疗及多学科综合治疗与生存预后密切相关。结论 对胰腺癌肝转移患者，疼痛、CA19-9≥1 000 u/ml及合并肝外转移提示预后不良。积极治疗、手术、介入化疗栓塞/介入化疗及多学科综合治疗可明显提高患者生活质量，延长生存时间
%K 胰腺癌
%K 肝转移
%K 多学科综合治疗
%K Efficacy of IMRT Combined with Capecitabine Concurrent Chemotherapy and High Intensity Focused Ultrasound for Elderly Patients with Non-operatable Pancreatic Cancer
%K Progress of miRNAs Related to Pancreatic Cancer
%K One Case Report of Ablation by Nano Knife on Unresectable Liver Metastases from Colon Cancer
%K Effect of ABCG2 Expression on Chemoresistance of Pancreatic Carcinoma Cell Line#br# SW1990
%K 125I Seed Implantation Combined with Chemotherapy for Colorectal Cancer with Postoperative Liver Metastasis
%K Review on Low-molecular-weight Heparin in Improving Prognosis of Pancreatic Cancer
%K Clinical Signifi cance of Decoy Receptor 3 Expression in Pancreatic Carcinoma
%K Role of Surgery for Limited Liver Metastases from Nasopharyngeal Carcinoma
%K Effects of SDF-1 and CXCR4 on HPA Expression in Liver Metastases Induced by Colorectal Cancer Cells
%K Correlation between miR-375 and PDK1 Expression in Pancreatic Cancer Tissues
%K Experimental Study on Inducing Apoptosis of Human Pancreatic Carcinoma Cells PANC-1 by Pseudomonas Aeruginosa Vaccinein in vitro
%K Effect of 5-Aza-CdR on Invasion and Migration of Pancreatic Carcinoma Cell Line PANC-1
%U http://www.zlfzyj.com/CN/abstract/abstract8420.shtml