%0 Journal Article %T Relationship of Visceral Adiposity Index with the Metabolic Phenotype and Cardiovascular Markers in Non-Diabetic Subjects | Insight Medical Publishing %A Elva Perez-Luque %A Gabriela Lopez-Moreno %A Herlinda Aguilar-Zavala %A Monica I Cardona-Alvarado %A Nicte Figueroa-Vega %J December, 2018 %D 2018 %R 10.21767/1791-809X.1000588 %X Aim: Visceral adiposity index (VAI) provides information of visceral adipose tissue function and insulin sensitivity. This study¡¯s aim is to evaluate the relationship of VAI with different metabolic phenotypes and cardiometabolic risk markers in non-diabetic subjects. Methods: 183 health clinical subjects from 30 to 50 years of age, with normal weight and with obesity grade I were recruited. Anthropometric measures were taken and quantified glucose, lipids, insulin, high-sensitivity Creactive protein (hs-CRP) and adiponectin concentrations. Unhealthy phenotype was defined according to the criteria; Visceral Adiposity index (VAI) was calculated. Results: 40% were metabolically healthy obese (MHO), they showed lower serum glucose, triglycerides, insulin, hs-CRP levels, systolic and diastolic blood pressure, HOMA-IR than metabolically unhealthy obese subjects (MUO). Metabolically unhealthy non-obese subjects (MUNO) showed higher serum triglycerides, insulin levels, HOMA- IR than the metabolically healthy non-obesity (MHNO) subjects. MUNO and MUO subjects had higher VAI values than MHNO and MHO subjects. In a logistic regression analysis using the cut-offs of VAI quartile 4, >2.25 in women and >1.86 in men found a strong association with glucose, HOMA-IR and adiponectin concentrations. In ROC analysis using these cut-off determined for glucose concentrations >100 mg/dL, an area under the curve of 0.83 in men and 0.71 in women; for HOMA-IR 0.78 only in men, and for adiponectin 0.69 in men and 0.91 in women. Conclusion: Therefore, VAI is a useful indicator to evaluate the metabolic risk both of non-obese and obese individuals. %U http://www.hsj.gr/medicine/relationship-of-visceral-adiposity-index-with-the-metabolic-phenotype-and-cardiovascular-markers-in-nondiabetic-subjects.php?aid=23549