%0 Journal Article
%T Synthesis and Toxicity of Complexes of Cu(II), Co(II) and Mn(II) with a
2(4-nitrophenyl)-4.5-diphenyl-1H-immidazole Ligand | Insight Medical Publishing
%A Arynta Dharmayanti
%A Fahimah Martak
%A Mohd Tajudin Mohd Ali
%A Rose Malina Annuur
%A Shinta Dwitifani Risqizia Poetri
%A Wahyu Prasetyo Utomo
%A Zjahra Vianita Nugraheni
%J Open Access statement:
%D 2018
%X Copper(II), cobalt(II), and manganese(II) complexes with 2(4-nitrophenyl)-4.5-diphenyl-1H-imidazole ligand have been successfully synthesized. The molecular formula for the formed complex compounds are [Cu(2(4-nitrophenyl)-4.5-diphenyl-1H-imidazole)2], [Co(2(4- nitrophenyl)-4.5-diphenyl-1H-imidazole)3] and [Mn(2(4-nitrophenyl)-4.5-diphenyl-1H-imidazole)3] complexes. This was confirmed by the results of the characterization of the CHN analyzer and AAS spectrometry. The FTIR characterization showed the presence of a distinct vibration spectrum of Cu-O, Co-O and Mn-O. Toxicity tests of the complex compounds [Cu(2(4-nitrophenyl)-4.5-diphenyl-1H-imidazole)2], [Co(2(4-nitrophenyl)-4.5- diphenyl-1H-imidazole)3] and [Mn(2(4-nitrophenyl)-4.5-diphenyl-1H-imidazole)3] was done with BSLT method and showed the LC50 values of 229.66 ppm; 265.79 ppm; 182.79 ppm meaning that [Mn(2(4-nitrophenyl)-4.5-diphenyl-1H-imidazole)3] is toxic compound.
%U http://www.ijddr.in/drug-development/synthesis-and-toxicity-of-complexes-of-cuii-coii-and-mnii-with-a24nitrophenyl45diphenyl1himmidazole-ligand.php?aid=22322