%0 Journal Article
%T The Surgical Management of Non-Functioning Pancreatic Neuro-
Endocrine Tumors | Insight Medical Publishing
%A Kyoichi Takaori
%A Shinji Uemoto
%A Takayuki Anazawa
%A Toshihiko Masui
%J January 2019
%D 2018
%X The incidence of pancreatic neuroendocrine tumors is increasing and the ratio of non-functioning tumors is gradually increasing due to progress in imaging technology. The definition of a non-functioning PNET is a tumor which presents without symptoms. These are potentially malignant and treatment is recommended according to size. The first choice for the treatment of a non-functioning pancreatic neuroendocrine tumor is resection. Localized, small, malignant non-functioning PNETs should be aggressively resected, while for small benign-appearing tumors the risks and the benefits of surgery should be carefully weighed. The surgical resection of liver metastases from non-functioning PNETs should be recommended if complete resection is possible. However, the benefit of surgical resection is limited compared to intra-arterial therapy if the tumor burden is high.
%U http://pancreas.imedpub.com/the-surgical-management-of-nonfunctioning-pancreatic-neuroendocrine-tumors.php?aid=21171