%0 Journal Article
%T 2-Aryldihydrobenzofuran Neolignans: Synthesis of Ficusal and Tomentosanan B | Insight Medical Publishing
%A Mohd Shukri Mat Ali
%A Nur Kartinee Kassim
%A Siti Fadilah Juhan
%A Siti Mariam Mohd Nor
%A Siti Munirah Mohd Faudzi
%J Der chemica Sinica
%D 2018
%X The synthesis of 2-aryldihydrobenzofurans, ficusal and tomentosanan B was achieved via two different cross-coupling methods between aryl or iodoaryl with coniferyl alcohol. Both Pd(OAc)2 catalysed coupling reactions were performed in the presence of base with or without ligand; an oxidant or phase transfer agent. Tomentosanan B was also obtained directly from the reduction of ficusal using NaBH4. The structures of these 2-aryldihydrobenzofuran neolignans were confirmed by 1D and 2D NMR and HRMS.
%U http://www.imedpub.com/articles/2aryldihydrobenzofuran-neolignans-synthesis-of-ficusal-and-tomentosanan-b.php?aid=22991