%0 Journal Article
%T New Synthetic Pathways for Thiocarbohydrazide
and Salicylaldehyde Azine Compounds
%J ISSN: Journal DOI: Frequency: Peer-review model: Digital Archiving: (ISSN: 2456-7795) Disclaimer:
%D 2017
%R 10.9734/AJOCS/2017/35504
%X Thiocarbohydrazide synthesis is an important intermediate step for many hydrazine organic synthetic reactions. Synthesis of thiocarbohydrazide can be done by reaction of carbon disulfide with hydrazine (hydrazinolysis) in water at 0ˇăC giving 25% yield (based on [hydrazine]). However, in this article, we achieve a 96% yield (based on [hydrazine]) by carrying out the reaction in methanol at 24ˇăC. The thiocarbohydrazide is then used to synthesize 1,5-bis (2-hydroxybenzaldehyde) dithiocarbohydrazone. By refluxing the latter compound in pyridine at 80ˇăC, it decomposes and rearranges to give salicylaldehyde azine.
%U http://www.sciencedomain.org/abstract/20454