%0 Journal Article
%T Improved outcomes after blastocyst-stage frozen-thawed embryo transfers compared with cleavage stage: a Society for Assisted Reproductive Technologies Clinical Outcomes Reporting System study - Fertility and Sterility
%A Banafsheh N. Kashani
%A Donald Alderson
%A Emily C. Holden
%A Pamela A. Ohman-Strickl
%A Peter G. McGovern
%A Sangita K. Jindal
%A Sara S. Morelli
%J Fertility and Sterility
%D 2018
%R https://doi.org/10.1016/j.fertnstert.2018.03.033
%X To investigate whether there is a difference in obstetrical and perinatal outcomes in blastocyst frozen-thawed embryo transfers (FETs) compared with cleavage-stage FET. A retrospective cohort study. Not applicable. Women undergoing autologous FETs at either the blastocyst stage (n = 118,572) or the cleavage stage (n = 117,619) reported to the Society for Assisted Reproductive Technology in the years 2004每2013. None. Live birth, gestational age, birth weight, miscarriage. After controlling for confounders, there were a 49% increased odds of live birth after blastocyst-stage FET compared with cleavage-stage FET (odds ratio [OR] = 1.49; 95% confidence interval [CI], 1.44, 1.54). Additionally, blastocyst FET was associated with a 68% (OR = 1.68; 95% CI, 1.63, 1.74) increased odds of clinical pregnancy and an 7% (OR = 0.93; 95% CI, 0.88, 0.92) decreased odds of miscarriage. There was also a 16% increased odds of preterm delivery (OR = 1.16; 95% CI, 1.06, 1.27) after blastocyst FET but no difference in birth weights. In patients undergoing FET, blastocyst-stage transfer is associated with higher live-birth rates when compared with cleavage-stage transfers. Furthermore, perinatal outcomes are similar between the groups. Mejores resultados despu谷s de transferencias de embriones congelados-descongelados en estadio de blastocisto en comparaci車n con embriones en estadio de segmentaci車n: Un estudio del Sistema de Informes de Resultados Cl赤nicos de la Sociedad para las Tecnolog赤as de Reproducci車n Asistida Investigar si existen diferencias en los resultados obst谷tricos y perinatales al comparar las transferencias de embriones congelados (TECs) en estadio de blastocisto vs las TEC en estadio de segmentaci車n. : Estudio retrospectivo de cohortes. No aplicable. Mujeres que se realizaron TECs aut車logas tanto en estadio de blastocisto (n=118572) como en estadio de segmentaci車n (n= 117619), cuyos ciclos fueron reportados a la Sociedad para la Tecnolog赤a de la Reproducci車n Asistida (Society for Assisted Reproductive Technology) durante los aˋos 2004-2013. Ninguna. Nacidos vivos, edad gestacional, peso al nacimiento, aborto. Despu谷s de controlar los factores de confusi車n, se observ車 un 49% m芍s de probabilidades de nacidos vivos despu谷s de TEC en estadio de blastocisto comparado con TEC en estadio de segmentaci車n (odds ratio [OR]= 1,49; intervalo de confianza del 95% [IC] 1,44; 1,54). Adem芍s, la TEC de blastocistos se asoci車 con un 68% (OR = 1,68; IC 95%; 1,63; 1,74) de incremento de las probabilidades de gestaci車n cl赤nica, y disminuyeron las probabilidades de aborto
%U https://www.fertstert.org/article/S0015-0282(18)30288-7/fulltext