%0 Journal Article
%T Illuminating pathogen¨Chost intimacy through optogenetics
%A Laura Thurow
%A Nishith Gupta
%A Ruben Dario Arroyo-Olarte
%A Vera Kozjak-Pavlovic
%J -
%D 2018
%R 10.1371/journal.ppat.1007046
%X The birth and subsequent evolution of optogenetics has resulted in an unprecedented advancement in our understanding of the brain. Its outstanding success does usher wider applications; however, the tool remains still largely relegated to neuroscience. Here, we introduce selected aspects of optogenetics with potential applications in infection biology that will not only answer long-standing questions about intracellular pathogens (parasites, bacteria, viruses) but also broaden the dimension of current research in entwined models. In this essay, we illustrate how a judicious integration of optogenetics with routine methods can illuminate the host¨Cpathogen interactions in a way that has not been feasible otherwise
%K Optogenetics
%K Host cells
%K Parasitic diseases
%K Cellular structures and organelles
%K Green fluorescent protein
%K Lipid metabolism
%K Chlamydia infection
%K Drug metabolism
%U https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1007046