%0 Journal Article %T Illustrative Application of the 2<sup>nd</sup>-Order Adjoint Sensitivity Analysis Methodology to a Paradigm Linear Evolution/Transmission Model: Point-Detector Response %A Dan Gabriel Cacuci %J American Journal of Computational Mathematics %P 355-381 %@ 2161-1211 %D 2020 %I Scientific Research Publishing %R 10.4236/ajcm.2020.103019 %X This work illustrates the application of the ¡°Second Order Comprehensive Adjoint Sensitivity Analysis Methodology¡± (2nd-CASAM) to a mathematical model that can simulate the evolution and/or transmission of particles in a heterogeneous medium. The model response is the value of the model¡¯s state function (particle concentration or particle flux) at a point in phase-space, which would simulate a pointwise measurement of the respective state function. This paradigm model admits exact closed-form expressions for all of the 1st- and 2nd-order response sensitivities to the model¡¯s uncertain parameters and domain boundaries. These closed-form expressions can be used to verify the numerical results of production and/or commercial software, e.g., particle transport codes. Furthermore, this paradigm model comprises many uncertain parameters which have relative sensitivities of identical magnitudes. Therefore, this paradigm model could serve as a stringent benchmark for inter-comparing the performances of all deterministic and statistical sensitivity analysis methods, including the 2nd-CASAM. %K Second-Order Adjoint Comprehensive Sensitivity Analysis Methodology (2< %K sup> %K nd< %K /sup> %K -CASAM) %K Evolution Benchmark Model %K Exact and Efficient Computation of First- and Second-Order Response Sensitivities %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=101648