%0 Journal Article
%T Synthesis and Crystal Structure Studies of Mitomycin C Dihydrate
%A Yingqi Feng
%A Yongshou Chen
%A Yixin Ren
%A Heng Zhang
%A Shuang Cao
%J Crystal Structure Theory and Applications
%P 13-21
%@ 2169-2505
%D 2020
%I Scientific Research Publishing
%R 10.4236/csta.2020.92002
%X The absolute configuration of mitomycin C was determined&nbsp;</span><span style=\"font-family:Verdana;\">by X-ray single crystal diffraction</span><span style=\"font-family:Verdana;\">&nbsp;(Cu</span><span style=\"font-family:Verdana;\">K</span><i><span style=\"font-family:Verdana;\">¦Á</span></i><span style=\"font-family:Verdana;\">), and a new&nbsp;</span><span style=\"font-family:Verdana;\">crystalline</span><span style=\"font-family:Verdana;\">&nbsp;dihydrate of mitomycin C had been prepared. The&nbsp;</span><span style=\"font-family:Verdana;\">experiment</span><span style=\"font-family:Verdana;\">&nbsp;result&nbsp;</span><span style=\"font-family:Verdana;\">provide</span><span style=\"font-family:Verdana;\">s</span><span style=\"font-family:Verdana;\">&nbsp;a definitive answer</span><span style=\"font-family:Verdana;\">&nbsp;to the real absolute configuration of mitomycin C and may put an end to the dispute&nbsp;</span><span style=\"font-family:Verdana;\">that baffle</span><span style=\"font-family:Verdana;\">s</span><span style=\"font-family:Verdana;\">&nbsp;researchers for decades</span><span style=\"font-family:Verdana;\">.&nbsp;</span><span style=\"font-family:Verdana;\">A</span><span style=\"font-family:Verdana;\">t the same time, some contentious structures</span><span style=\"font-family:Verdana;\">&nbsp;</span><span style=\"font-family:Verdana;\">about the mitomycin C in&nbsp;</span><i><span style=\"font-family:Verdana;\">American Pharmaco</span></i><i><span style=\"font-family:Verdana;\">p</span></i><i><span style=\"font-family:Verdana;\">oeia</span></i><i><span style=\"font-family:Verdana;\">&nbsp;</span></i><i><span style=\"font-family:Verdana;\">USP</span></i><span style=\"font-family:Verdana;\">36</span><i><span style=\"font-family:Verdana;\">-NF</span></i><span style=\"font-family:Verdana;\">31</span><span style=\"font-family:Verdana;\">,&nbsp;</span><i><span style=\"font-family:Verdana;\">Chinese pharmacopoeia</span></i><i><span style=\"font-family:Verdana;\">&nbsp;</span></i><span style=\"font-family:Verdana;\">2015</span><i><span style=\"font-family:Verdana;\">&nbsp;edtion</span></i><span style=\"font-family:Verdana;\">&nbsp;and numbers of&nbsp;</span><span style=\"font-family:Verdana;\">literature</span><span style=\"font-family:Verdana;\">s are marked. The absolute configuration&nbsp;</span><span style=\"font-family:Verdana;\">is&nbsp;</span><span style=\"font-family:Verdana;\">also verified</span><span style=\"font-family:Verdana;\">&nbsp;by</span><span style=\"font-family:Verdana;\">&nbsp;</span><span
%K Crystal Structure
%K Dihydrate
%K Absolute Configuration
%K Mitomycin C
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=99142