%0 Journal Article
%T Assessment of Serum Electrolyte Levels & HbA1C Levels among Type 2 Diabetic Sudanese Patients with Macrovascular Complications in Khartoum State
%A Ragda Hafaz Ramadan
%A Abdulmwla Muhammed Abdullah
%J Open Access Library Journal
%V 7
%N 3
%P 1-9
%@ 2333-9721
%D 2020
%I Open Access Library
%R 10.4236/oalib.1106110
%X Background: Recently epidemiological studies have shown that type 2 diabetes mellitus is great a risk factor for cardiovascular mortality. Electrolyte abnormalities are commonly encountered in chronic diabetes mellitus type 2 patients. Aim: The aim of this study was to estimate serum electrolyte levels & HbA1C levels among Sudanese diabetic Patients with macrovascular complications in Khartoum State, Sudan. Materials & Methods: In this case, control hospital based study conducted in Khartoum state. Hundred subjects were involved; fifty were type 2 diabetes patients and fifty healthy subjects control group sex and age matched. Serum Na and K levels were estimated by Automated Biochemistry Analyzer (Easylyte electrolyte) and HbA1C by Automated Biochemistry Analyzer (Mindary Bs380). Result: The mean serum level of sodium and potassium in type 2 diabetes patients was significantly decreased (137.7 ¡À 4.05 vs 139.8 ¡À 3.62 mmol/l, p = 0.008 and 3.60 ¡À 0.20 vs 3.92 ¡À 0.22 mmol/l, p = 0.03 respectively). Whereas, HA1C level showed significant increases in the test group when compared with reference group (9.68 ¡À 1.24 vs 5.44% ¡À 0.42%, p = 0.000). Across gender, our study observed no significant alteration in serum Na and K levels (p > 0.05) in type 2 diabetic patients. Furthermore, serum Na  level was significantly correlated with K  (R = 0.369, p = 0.008). Whereas, both Na  and K  were in significantly correlated with patients age, HbA1c (%), and duration of DM (p > 0.05). In contrast, HA1C is significantly correlated with the duration of diabetes (R = 0.425, p = 0.002). Conclusion: Our study revealed significant alterations in electrolyte levels in type 2 diabetes mellitus and proper hyperglycemic control with evaluation of electrolyte levels can reduce the complication accompanied with electrolyte disbalance in type 2 DM.
%K Electrolyte
%K HbA1C
%K Sodium
%K Potassium
%K Macro Vascular Complications
%K Sudanese
%U http://www.oalib.com/paper/5426894