%0 Journal Article
%T Correlation of Invasively Estimated Left Ventricular End Diastolic Pressure with Acceleration of E¡¯ Wave by Tissue Doppler Imaging of Mitral Annulus
%A Mahmoud Kamel
%A Morad Beshay
%A Said Shalaby
%A Ahmed Emara
%A Mohammed Abdel Rahman
%J World Journal of Cardiovascular Diseases
%P 681-691
%@ 2164-5337
%D 2019
%I Scientific Research Publishing
%R 10.4236/wjcd.2019.99061
%X <strong>Background: </strong><span style=\"line-height:1.5;font-family:Verdana;\">There is no single noninvasive index that provides a direct measure of LV filling pressure. However, invasive measuring of LV end diastolic pressure (LVEDP) provides reliable assessment of LV diastolic dysfunction, but its invasive nature limits its use in daily practice. Accurate noninvasive assessment of LV diastolic dysfunction is highly desirable, and the relationship between the degree of LVEDP and acceleration of E¡¯ wave obtained by tissue Doppler imaging (TDI) of mitral annulus is not clearly assessed; here in our study we aimed to assess the relation between the degree of LVEDP and the acceleration rate of E¡¯ wave of mitral annular Doppler tissue.</span><span style=\"line-height:1.5;font-family:Verdana;\"> </span><b style=\"line-height:1.5;\"><span style=\"font-family:Verdana;\">Patients and Methods: </span></b><span style=\"line-height:1.5;font-family:Verdana;\">The study included 60 patients divided equally into 3 groups according to the degree of LVEDP, group I (Normal):</span><span style=\"line-height:1.5;font-family:Verdana;\"> </span><span style=\"line-height:1.5;font-family:Verdana;\">&lt;10 mmHg, group II (Grey zone): 10 - 14 mmHg, and group III (Elevated): ¡Ý15 mmHg. All participants underwent Electrocardiographic examination (ECG), standard two-dimensional echocardiography, mitral Doppler flow and tissue Doppler imaging of mitral annulus including E/E</span><span style=\"line-height:1.5;font-family:Verdana;\">¡¯ </span><span style=\"line-height:1.5;font-family:Verdana;\">ratio and E</span><span style=\"line-height:1.5;font-family:Verdana;\">¡¯ </span><span style=\"line-height:1.5;font-family:Verdana;\">wave acceleration rate</span><span style=\"line-height:1.5;font-family:Verdana;\">. Coronary angiography and left sided heart catheterization and measuring LVEDP were performed for correlating E</span><span style=\"line-height:1.5;font-family:Verdana;\">¡¯</span><span style=\"line-height:1.5;font-family:'';\"><span style=\"font-family:Verdana;\"> wave acceleration rate with invasively estimated LVEDP.&nbsp;</span><b><span style=\"font-family:Verdana;\">Results</span></b><span style=\"font-family:Verdana;\">: There was significant progressive decrease in E¡¯ acceleration rate (E¡¯</span></span><span style=\"line-height:1.5;font-family:Verdana;\"> </span><span style=\"line-height:1.5;font-family:Verdana;\">Acc rate) with progressive increase in LVEDP from I to III (P 0.001), while there was significant progressive increase in E/E¡¯ ratio with progressive increase in
%K LV End Diastolic Pressure
%K E Annular Wave Acceleration
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=95288