%0 Journal Article
%T Prognostic Value of Serum Uric Acid Level in Patients with ST Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention
%A Mohamed Mahmoud Mohamed Abdellatif
%A Ahmed Abdel-Galeel
%A Mohamad A. Alsherif
%A Salwa Demtry
%J World Journal of Cardiovascular Diseases
%P 584-599
%@ 2164-5337
%D 2019
%I Scientific Research Publishing
%R 10.4236/wjcd.2019.98051
%X <strong>Background:</strong><span style=\"line-height:1.5;font-family:Verdana;\"> Serum uric acid (SUA) has been correlated with cardiac morbidity and mortality. However, its prognostic value in acute ST-segment </span><span style=\"line-height:1.5;font-family:Verdana;\">elevation myocardial infarction (STEMI) </span><span style=\"line-height:1.5;font-family:Verdana;\">is </span><span style=\"line-height:1.5;font-family:Verdana;\">still uncertain. The aim of this study was to evaluate the prognostic value of SUA on admission in patients with STEMI undergoing primary percutaneous coronary intervention (PPCI).</span><span style=\"line-height:1.5;font-family:Verdana;\"> </span><b style=\"line-height:1.5;\"><span style=\"font-family:Verdana;\">Methods:</span></b><span style=\"line-height:1.5;font-family:Verdana;\"> We prospectively enrolled 150 STEMI patients underwent PPCI. The mean age of the studied population was 56.1 years, 78%&nbsp;were males&nbsp;while 22% were females. Patients were divided into tertiles based on the basal serum uric acid level. Patients with high SUA (n</span><span style=\"line-height:1.5;font-family:Verdana;\"> </span><span style=\"line-height:1.5;font-family:Verdana;\">= 72) was defined as a value in the third tertile (&gt;6.4 mg/dl), and a low SUA group (n</span><span style=\"line-height:1.5;font-family:Verdana;\"> </span><span style=\"line-height:1.5;font-family:Verdana;\">=</span><span style=\"line-height:1.5;font-family:Verdana;\"> </span><span style=\"line-height:1.5;font-family:Verdana;\">78) was set as a value in the lower two tertiles (&lt;6.4 mg/dl). Clinical characteristics, angiographic findings, echocardiographic data, in-hospital and three-month outcomes of PPCI were analyzed.</span><span style=\"line-height:1.5;font-family:Verdana;\"> </span><b style=\"line-height:1.5;\"><span style=\"font-family:Verdana;\">Results:</span></b><span style=\"line-height:1.5;font-family:'';\"><span style=\"font-family:Verdana;\"> SUA level on admission carried prognostic value in patients with STEMI undergoing PPCI where the low uric acid group had better KILLIP class (</span><i><span style=\"font-family:Verdana;\">P</span></i></span><i style=\"line-height:1.5;\"><span style=\"font-family:Verdana;\"> </span></i><span style=\"line-height:1.5;font-family:Verdana;\">=</span><span style=\"line-height:1.5;font-family:'';\"></span><span style=\"line-height:1.5;font-family:'';\"><span style=\"font-family:Verdana;\">0.001), better TIMI flow (</span><i><span style=\"font-family:Verdana;\">P</span></i></span><i style=\"line-height:1.5;\"><span
%K Uric Acid
%K Primary Angioplasty
%K STEMI
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=94464