%0 Journal Article %T Transcranial Doppler Ultrasonography to Prevent Cerebrovascular Accident in Children with Sickle-Cell Disease %A Giuliana Carpentieri-Pipolo %A Marcelo de Lima Oliveira %A Fernando Mendes Paschoal Junior %A Edson Bor-Seng-Shu %J Neuroscience & Medicine %P 162-173 %@ 2158-2947 %D 2019 %I Scientific Research Publishing %R 10.4236/nm.2019.102011 %X Sickle-cell disease (SCD) is the most common cause of ischemic stroke in children and it happens in about 11% of patients between the age of 2 and 20 years old. About 7% of the world population is affected by hemoglobin disorders, mostly sickle cell anemia. SCD has a high prevalence in the population of African offspring and it is a public health problem in Brazil that affects more than 30,000 million people. Prevention of primary stroke might be feasible with a way to identify children at greatest risk. Transcranial Doppler Ultrasonography (TCD) to SCD patients can be a valuable service that results in a significant decrease of first stroke rates. In this work, we present a review about TCD as an effective strategy to detect children with SCD who are at risk for stroke. %K Transcranial Doppler %K Sickle Cell Disease %K Stroke in Children %K Cerebrovascular Disease %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=92930