%0 Journal Article
%T Correlation of Combined Characters of Amino Acid and Whole Protein with Success Rate of Crystallization of <i>Lactobacillus</i> Proteins
%A Shaomin Yan
%A Guang Wu
%J Journal of Biomedical Science and Engineering
%P 245-256
%@ 1937-688X
%D 2019
%I Scientific Research Publishing
%R 10.4236/jbise.2019.124017
%X Crystallization of proteins is a very delicate process, which is influenced by many known and unknown factors. Of tested factors, many factors are exclusively related to individual amino-acid characters such as molecular weight or protein characters such as protein length. It is considered necessary to test factors that combine both individual amino-acid characters and protein characters with respect to success rate of crystallization. In this study, two combined characters characterizing individual amino-acid character and protein character, amino acid distribution probability and future composition, were used to correlate the success rate of crystallization of proteins from<em> Lactobacillus</em> via modeling. The results obtained from logistic regression and neural network were compared against the results obtained from each of 533 individual amino-acid characters. This study demonstrated that the combined characters are involved in crystallization process and should be taken into account for predicting the success rate of crystallization process.
%K Amino Acid Character
%K Distribution Probability
%K Future Composition
%K &lt
%K i&gt
%K Lactobacillus&lt
%K /i&gt
%K Protein Crystallization
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=92102