%0 Journal Article
%T PPDO滑扣型血管支架制备方法与性能研究<br>Investigation of Preparations and Characters of PPDO Slide Fastener Type Stents
%A 李瑜
%A 卞平艳
%A 童景琳
%J 机械科学与技术
%D 2015
%X 比较成形工艺对聚对二氧环已酮(PPDO)滑扣式可降解血管支架性能的影响。对微压印和3D打印(3DP)两种聚合物成形工艺进行比较,主要包括其成形表面质量和径向强度两方面。试验结果显示:微压印制备支架内表面Ra0.429、外表面Ra1.24,优于3DP制备支架,而支架内外表面质量的差异化与可控性也更适合血管支架在抑制凝血和置放稳定等临床医学的需要;另外,两种制备方法所制支架的径向强度均高于临床需要的80 kPa的标准,其中微压印比3DP略高4%。原因可能是微压印制备将PPDO材料的成形温度降低在材料粘流态温度范围内,使该高分子材料的热降解大大降低,较好的保留了原材料的力学性能与强度保障时间。<br>Two preparations of the PPDO(Poly p-dioxanone) degradable vascular stents, micro-imprint and 3D Printing was investigated. And each type samples' characters were studied, such as surface quality and radial strength. The results showed that, the surface quality of micro-imprint samples appears a group of average dates, inner surface Ra 0.429 and outside surface Ra 1.24, which is superior to the 3D Printing ones. And the diversity and controllability of the inner and outside surface quality, is more meet the clinical medicine requirement in the sections of inhibiting blood coagulation and steady placement. In addition, the intensity of radial strength of two kinds samples are higher than the clinical requirement(80 kPa), and the micro-imprint one is slightly higher than that of 3D Printing by 4%. This phenomenon was attributed to the forming temperature. In the micro-imprint process, the PPDO was fabricated in the viscous state, which made the thermal degradation of the polymer materials greatly reduced, better retention of mechanical properties and guarantee time of strength
%K 聚对二氧环己酮
%K 血管支架
%K 微压印
%K 3D打印
%K 粘流态&lt
%K br&gt
%K 3D Printing
%K blood
%K intravascular stents
%K measurements
%K mechanical properties
%K micro-imprint
%K Poly p-dioxanone(PPDO)
%K polymers
%K surface properties
%K surface roughness
%K temperature
%K viscous state
%U http://journals.nwpu.edu.cn/jxkxyjs/CN/abstract/abstract5893.shtml