%0 Journal Article
%T 葡萄糖调节蛋白78与肿瘤耐药和靶向治疗进展<br>Research progress on glucose-regulated protein 78 in drug resistance and targeted therapy for cancer
%A 郑以孜
%A 邵志敏&lt
%A br&gt
%A ZHENG Yizi
%A SHAO Zhimin
%J 中国癌症杂志
%D 2018
%R 10.19401/j.cnki.1007-3639.2018.02.013
%X 葡萄糖调节蛋白78(glucose-regulated protein 78，GRP78)在肿瘤耐药发生中具有重要作用，针对GRP78的靶向治疗已成为抗癌治疗的研究热点。该研究简要介绍了葡萄糖调节蛋白78，总结其与化疗、内分泌治疗、靶向治疗等治疗耐药的关系以及耐药机制，同时总结了GRP78靶向治疗方面的研究进展。<br
%K 葡萄糖调节蛋白78
%K 肿瘤
%K 耐药
%K 靶向治疗
%K &lt
%K br&gt
%K Glucose-regulated protein 78
%K Cancer
%K Drug resistance
%K Targeted therapy
%U http://www.china-oncology.com/CN/abstract/abstract975.shtml