%0 Journal Article
%T Frontal Analysis Continuous Capillary Electrophoresis Study on the Interaction of an Amphiphilic Alternating Copolymer with Triton X-100
%A Akihito Hashidzume
%A Takuya Shimomachi
%A Takahiro Sato
%J International Journal of Analytical Chemistry
%D 2011
%I Hindawi Publishing Corporation
%R 10.1155/2011/617981
%X The interaction of amphiphilic alternating copolymers of sodium maleate and dodecyl vinyl ether (Mal/C12) with a nonionic surfactant, Triton X-100 (TX), was investigated by frontal analysis continuous capillary electrophoresis (FACCE). The binding isotherms obtained from FACCE data were indicative of weak cooperative interaction for all the polymers examined. The cooperative interaction was also analyzed by the Hill model, and the results were compared with the previous results on the interaction of statistical copolymers of sodium 2-acrylamido-2-methylpropanesulfonate and N-dodecylmethacrylamide with TX. 1. Introduction Interactions between amphiphilic polymers and surfactants have attracted increasing interest from researchers in the last two or three decades because they are considered as simple model systems for colloid-colloid interactions, which are important in biological systems and various applications [1每7]. The interactions of amphiphilic polymers with surfactants have been investigated so far by various techniques [1], including equilibrium dialysis [8, 9], turbidimetry [10每12], viscometry [10, 13, 14], light scattering [10, 15], and fluorescence [10, 13, 15每17]. Frontal analysis continuous capillary electrophoresis (FACCE) is a powerful tool to investigate the association equilibrium of colloidal species because it allows ones to obtain binding isotherms, which are fundamental data for detail understanding on colloid-colloid interactions, in a short time period using a small amount of samples [18]. FACCE has been utilized mainly for binding equilibrium of protein-polymer systems [19每28]. To our knowledge, however, FACCE studies on the polymer-surfactant interaction have been still scarce [29, 30]. In the preceding study, the interaction of statistical copolymers of sodium 2-acrylamido-2-methylpropanesulfonate and N-dodecylmethacrylamide {A/C12(x), where x denotes the mol% content of N-dodecylmethacrylamide} with a nonionic surfactant, Triton X-100 (TX, Scheme 1), was investigated by FACCE [29]. The binding isotherms obtained using the FACCE data indicated that the binding of TX was weakly cooperative for the whole x range (x = 10每60 mol%) and A/C12(x) polymers of x > ca. 50ˋmol% exhibited higher cooperativity than did A/C12(x) copolymers of x < ca. 40ˋmol%. In this work, we have further studied on the interaction of an alternating copolymer of sodium maleate and dodecyl vinyl ether (Mal/C12, Scheme 1) with TX and compared the Mal/C12-TX interaction with the our previous study in order to investigate the effect of the polymer structure on
%U http://www.hindawi.com/journals/ijac/2011/617981/