%0 Journal Article
%T 碲化镉量子点与朊蛋白相互作用研究<br>Study on the Interaction of CdTe Quantum Dots with Prion Protein
%A 张凌燕
%A 隆异娟&lt
%A br&gt
%A ZHANG Ling-yan
%A LONG Yi-juan
%J 西南大学学报(自然科学版)
%D 2018
%R 10.13718/j.cnki.xdzk.2018.03.019
%X 碲化镉量子点(CdTe QDs)与重组型朊蛋白(rPrP)相互作用时，rPrP会诱导CdTe QDs发生聚集，引起CdTe QDs荧光显微镜成像、紫外-可见吸收光谱和荧光光谱发生改变.而CdTe QDs会加速rPrP纤维化，引起硫磺素T(ThT)荧光明显增强和刚果红(Congo Red)紫外-可见吸收光谱红移.<br>When CdTe QDs interact with rPrP, the latter will induce CdTe QDs aggregates, thus resulting in changes of CdTe QDs fluorescent microscopic imaging, UV-Vis absorption spectra and fluorescence spectra. Meanwhile, CdTe QDs can accelerate rPrP fibrosis, causing obvious enhancement of thioflavine T fluorescence and inducing a red shift of the Congo Red UV-Vis absorption spectra
%K 量子点
%K 朊蛋白
%K 聚集
%K 纤维化&lt
%K br&gt
%K quantum dot
%K prion protein
%K aggregation
%K fibrosis
%U http://xbgjxt.swu.edu.cn/jsuns/html/jsuns/2018/3/201803019.htm