%0 Journal Article %T A型肉毒杆菌毒素在口腔颌面部的临床应用<br>Clinical application of botulinum toxin type A in oral and maxillofacial region %A 佘杨杨 %A 农晓琳 %J 国际口腔医学杂志 %D 2017 %R 10.7518/gjkq.2017.06.016 %X 摘要: A型肉毒杆菌毒素(BTX-A)是肉毒杆菌产生的一种细菌外毒素,通过抑制神经-肌肉接头处乙酰胆碱的释放而发挥作用。近年来研究发现,BTX-A可应用于口腔颌面部整形美容及一些口腔疾病的治疗,为口腔疾病替代治疗提供了新方法和新方向。本文综述了BTX-A的作用机制、在口腔颌面部的临床应用、禁忌证、操作注意事项、并发症及治疗。<br>Abstract: Botulinum toxin type A(BTX-A) is a kind of exotoxin produced by the bacterium Clostridium botulinum which works by inhibiting the release of acetylcholine at the neuromuscular junction. Recent studies have found that BTX-A can be used in the oral and maxillofacial plastic surgery and the treatment of some oral diseases, providing a new method and a new direction for alternative treatment of oral diseases. The present review focuses on the mechanism, clinical application in the oral and maxillofacial region, operation cautions, contraindications and treatment of BTX-A.<br>中图分类号 %K A型肉毒杆菌毒素 %K 口腔颌面部 %K 临床应用 %K < %K /br> %K botulinum toxin type A %K oral and maxillofacial region %K clinical application %U http://www.gjkqyxzz.cn/CN/10.7518/gjkq.2017.06.016