%0 Journal Article
%T 胰腺肿瘤干细胞研究进展
%A 石小军综述
%A 江华
%A 审校
%J 同济大学学报(医学版)
%D 2016
%R 10.16118/j.1008-0392.2016.04.024
%X 胰腺导管腺癌(pancreatic ductal adenocarcinoma, PDAC)是最常见的胰腺癌病理类型,亦是预后最差的恶性肿瘤。近年来胰腺肿瘤干细胞(pancreatic cancer stem cell, PCSC)的研究取得了诸多进展,PCSC与胰腺肿瘤的侵袭、转移及复发都有着直接联系。本研究将从PCSC的相关标志物、肿瘤微环境及靶向治疗等角度对近年来PCSC的相关研究进展作一综述。</br>Pancreatic ductal adenocarcinoma(PDAC) is the most common histopathological type of pancreatic cancer with a poor prognosis. Pancreatic cancer stem cell(PCSC) are considered a direct connection with the invasion, metastasis and recurrence of PDAC. This article reviews the recent research progress on the bio-markers, tumor microenvironment of PCSC and it's potential application in targeted therapy
%K 胰腺肿瘤 肿瘤干细胞 标志物 肿瘤微环境&lt
%K /br&gt
%K pancreatic cancer cancer stem cells bio-markers tumor microenvironment
%U http://tjyxxb.cnjournals.cn/ch/reader/view_abstract.aspx?file_no=20160424&flag=1