%0 Journal Article %T Synthesis and Neuroprotective Activity of Neolamellarin A Analogues Synthesis and Neuroprotective Activity of Neolamellarin A Analogues %A ZHANG Meng %A YIN Ruijuan %A ZHANG Yiran %A HAO Cui %A ZHANG Lijuan %A JIANG Tao %J 中国海洋大学学报(英文版) %D 2018 %X Alkaloids are a class of natural products with a wide range of biological activities. Due to the special living environment, the alkaloids from marine sponges have exhibited different biological activities and promising medical application potential. Neolamellarin A is a marine alkaloid possessing bisaryl-pyrrole structural features. Here, the synthesis of 12 different 3,4-bisaryl-N-alkylated permethylated analogues of neolamellarin A and their outstanding neuroprotective activity in PC12 cells are presented and discussed %U http://qdhb.cbpt.cnki.net/WKD/WebPublication/paperDigest.aspx?paperID=4db40ce0-8e73-4f61-bca2-343d336b6c50