%0 Journal Article
%T 间充质干细胞来源外泌体在氧化应激损伤中的研究进展
%A 翟骁
%A 王一然
%A 朱明向
%A 王奇金
%J 第二军医大学学报
%D 2018
%R 10.16781/j.0258-879x.2018.07.0716
%X 氧化应激损伤是导致疾病的一个重要因素。间充质干细胞来源外泌体（MSC-exo）含有多种蛋白质、脂质、编码RNA及非编码RNA，可通过多种途径减轻机体的氧化应激损伤，促进受损的组织细胞修复再生，因此MSC-exo在氧化应激所致疾病的治疗中有巨大的发展潜力。本文对MSC-exo在减轻氧化应激导致的心血管损伤、肺组织损伤、肾脏损伤、肝细胞损伤等方面的研究进展作一综述。</br>Oxidative stress damage is known to be a major factor leading to many diseases. Mesenchymal stem cell-derived exosomes (MSC-exos) are enriched with various proteins, lipids, coding RNAs and non-coding RNAs, and alleviate oxidative stress damage and stimulate the regeneration response of damaged tissues and cells. MSC-exos hold a great potential for the treatment of diseases caused by oxidative stress. In this review, we summarized the research progress of MSC-exos in cardiovascular injury, lung injury, kidney injury and liver cell injury caused by oxidative stress
%K 间充质干细胞 外泌体 氧化性应激 损伤修复&lt
%K /br&gt
%K mesenchymal stem cells exosomes oxdative stress damage repair
%U http://www.ajsmmu.cn/ajsmmu/ch/reader/view_abstract.aspx?file_no=20170381&flag=1