%0 Journal Article
%T 药物代谢组学在肿瘤诊治中的应用与研究进展
%A 文柳静
%A 王晨
%J 中国药科大学学报
%D 2015
%X 随着代谢组学和现代分析技术、生物信息学技术的不断发展，药物代谢组学在肿瘤诊治方面的应用也日益成为研究热点，特别是在肿瘤药物疗效判断、毒性作用、耐药预测、个性化用药以及肿瘤标志物发现上有着重要作用。本文就药物代谢组学的概念、研究方法及其在肿瘤诊治中的应用等方面的研究进展进行综述。</br>With the development of metabonomics and modern instrumental analysis and bioinformatics, pharmaco-metabonomics has been rapidly put into the diagnosis and treatment of tumor, with a particularly important role in the evaluation and prediction of efficacy, toxicity and resistance of anti-tumor drugs, indivisualized medication and detection of tumor markers. This paper reviews the concept and methodologies of pharmaco-metabonomics, as well as the latest research advances of pharmaco-metabonomics in the diagnosis and freatment of tumors
%K 代谢组学 药物代谢组学 肿瘤 耐药 毒性 个性化用药&lt
%K /br&gt
%K metabonomics pharmaco-metabonomics tumor drug resistance toxicity indivisualized medication
%U http://www.zgykdxxb.cn/jcpu/ch/reader/view_abstract.aspx?file_no=20150403&flag=1