%0 Journal Article
%T Omega-3脂肪酸与心血管疾病<br>#br# Omega-3 fatty acids and cardiovascular diseases
%A 程 棣
%A 林 琳
%A 杜 瑞
%A 陆洁莉&lt
%A br&gt
%A CHENG Di
%A LIN Lin
%A DU Rui
%A LU Jie-li
%J 上海交通大学学报（医学版）
%D 2016
%R 10.3969/j.issn.1674-8115.2016.08.024
%X Omega-3系列多不饱和脂肪酸为人体自身不能合成的必需脂肪酸，对人体的作用与二十碳五烯酸（EPA）、二十二碳六烯酸（DHA）的生物活性密切相关。大量研究表明，omega-3脂肪酸具有改善心血管疾病的作用。然而近年来，部分人体研究得出了与此不同的结论。该文回顾了omega-3脂肪酸的主要食物来源、合成路径，并进一步探讨了其对于心血管危险因素的影响、对心血管疾病作用的临床证据及作用机制。<br>： Omega-3 polyunsaturated fatty acids are essential fatty acids that cannot be synthesized in human body. The effects of omega-3 fatty acids are closely associated with the bioactivity of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Considerable research suggested that omega-3 fatty acids can improve the cardiovascular diseases. However, some studies obtained conflictive results in recent years. This article reviews major dietary sources and synthesis pathways of omega-3 fatty acids and discusses their effects on cardiovascular risk factors, the clinical evidence of cardiovascular protective effect, as well as mechanisms
%K omega-3
%K 二十二碳六烯酸
%K 二十碳五烯酸
%K 心血管疾病
%K &lt
%K br&gt
%K omega-3
%K docosahexaenoic acid
%K eicosapentaenoic acid
%K cardiovascular disease
%U http://xuebao.shsmu.edu.cn/CN/abstract/abstract11268.shtml